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(A) Effects of shikonin on TLR4 expression and NF-κB activation in liver tissues. (B) Effects of shikonin on TLR4 expression and NF-κB activation in LPS-stimulated RAW264.7 cells. The values presented are the mean ±S.E.M. of three independent experiments. The density values of the Western blot were normalized for β-actin. P#<0.01 vs. control group, P*<0.05, P**<0.01 vs. LPS/GalN group.
