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(A) MTT assay results showed that Aβ inhibited the viability of SH-SY5Y cells and downregulation of BACE1 enhanced the inhibitory effects of Aβ. (B) Downregulation of miR-15b relieved Aβ-induced viability inhibition of SH-SY5Y cells. (C) Flow cytometric analysis results showed that Aβ-induced apoptosis of SH-SY5Y cells and downregulation of BACE1 enhanced the induced effects of Aβ. (D) Downregulation of miR-15b decreased apoptosis of SH-SY5Y cells in the presence of Aβ.
