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. 2017 Nov 17;23:799–809.

Table 2. CNTF concentrations in the biologic fluids (pg/ml) and the aqueous humor to lacrimal fluid ratio in cataract patients with and without POAG.

Biologic fluid Cataract and POAG group (n=55) Cataract group
          (n=61a) P
          Aqueous humor
     mean±SD
 39.9±26.2
 57.2±25.6
 <0.001
     range
 3.4–135.2
 7.0–135.2
            
     median (IQR)
 36.6 (24.5–47.7)
 57.0 (38.0–72.8)
            
          Lacrimal fluid
     mean±SD
 25.7±14.9 b
 39.9±18.0
 <0.001
     range
 3.2–84.4
 4.6–92.4
            
     median (IQR)
 23.8 (17.6–31.4)
 38.4 (28.2–50.2)
            
          Aqueous humor / lacrimal fluid ratio
     mean±SD
 1.69±1.05 b
 1.58±0.70
 NS
     range
 0.45–6.88
 0.33–4.33
            
     median (IQR)
 1.48 (1.15–1.82)
 1.47 (1.09–1.82)
            
          Blood serum
     mean±SD
 5.45±4.72
 5.96±4.92
 NS
     maximum
 20.30
 29.50
            
     median (IQR)
 4.12 (2.49–6.83)
 4.59 (2.82–7.47)
            
     n / n censored 55 / 10 57 / 7            

Statistical analysis was performed by Mann–Whitney U test; CNTF in blood serum was compared by the generalized Wilcoxon test POAG – primary open-angle glaucoma; SD – standard deviation; IQR – interquartile range; n censored - number of observations below the minimum quantifiable value 2.5 pg/ml; NS – non-significant a For blood serum n=57 b n=53 (two cases excluded with CNTF in lacrimal fluid not examined)