Table 3. Age and gender characteristics, IOP, medical, laser, and surgical treatment in the main group depending on the POAG stage.
Variable | POAG stage |
P |
||
---|---|---|---|---|
1/2. Early to moderate (n=21) | 3. Advanced (n=18) | 4. Severe (n=16) | ||
Age | ||||
mean±SD |
73.3±6.0 |
74.2±5.9 |
69.1±5.9 |
0.031 a |
range |
55–83 |
60–84 |
58–79 |
|
median (IQR) |
73.0 (71–78) |
75.5 (71–78) |
70.5 (64.8–74) |
|
Sex | ||||
Women, n (%) |
15 (71%) |
11 (61%) |
6 (37.5%) |
|
IOP, mmHg | ||||
mean±SD |
17.6±3.7 |
18.4±4.1 |
15.2±4.2 |
|
range |
8–25 |
7–25 |
10–23 |
|
median (IQR) |
17 (16–19) |
19 (17–20.5) |
14 (11–19) |
|
Medications, n (%) | ||||
β-blockers |
15 (71%) |
15 (83%) |
10 (63%) |
|
Prostaglandin
analogs |
7 (33%) |
6 (33%) |
10 (63%) |
|
Topical
carbonic
anhydrase
inhibitors |
8 (38%) |
5 (28%) |
2 (13%) |
|
α2-adrenergic
agonists |
- |
4 (22%) |
1 (6%) |
0.044 b |
Laser treatment and surgery | ||||
SLT |
3 (14%) |
1 (6%) |
1 (6%) |
|
NPDS |
7 (33%) |
7 (39%) |
6 (38%) |
|
NPDS+deferr ed Nd:YAG goniopuncture | 3 (14%) | 5 (28%) | 4 (25%) |
a Kruskal–Wallis test; b Fisher's exact test POAG – primary open-angle glaucoma; SD – standard deviation; IQR – interquartile range; IOP – intraocular pressure; SLT – selective laser trabeculoplasty; NPDS – nonpenetrating deep sclerectomy