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Composition and concentration levels employed in full range design of experiment.
| Parameter | Substance | Lower limit fasted | Upper limit fed |
|---|---|---|---|
| Bile salt (mM) | Sodium taurocholate | 1.5 | 24 |
| Lecithin (mM) | Phosphatidylcholine | 0.2 | 4.8 |
| Fatty acid (mM) | Sodium oleate | 0.5 | 52 |
| pH | Sodium hydroxide/hydrochloric acid | 5 | 7 |
| Salt (mM) | Sodium chloride | 68 | 203 |
| Buffer (mM) | Phosphatea | 15 | 45 |
| Monoglyceride (mM) | Glyceryl mono-oleate | 0.5 | 6.5 |
Monophosphate buffer (KH2PO4).
