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. 2017 Dec 1;12(12):e0188473. doi: 10.1371/journal.pone.0188473

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© 2017 Lozano-Velasco et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 4 — Redox signaling gene expression analyses of adult left atria (LA) corresponding to NppaCre⁺Pitx2^-/- (A), HTD (B) and SHR (C), respectively, as compared to their corresponding controls. Note that Cat, Gpx1 and Sod2 are significantly decreased in NppaCre⁺Pitx2^-/- as compared to NppaCre^-Pitx2^fl/fl controls, Cat and Sod2 are significantly increased in HTD mice whereas no changes are observed in SHR mice. In all cases, n = 6. *p<0.01, ***p<0.001, ****p<0.0001.