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. 2014 May 8;15(3):93–101. doi: 10.1120/jacmp.v15i3.4641

Table 4.

OAR sparing comparison

p‐value
CRT IMRT VMAT CRT vs. IMRT CRT vs. VMAT IMRT vs. VMAT
Cord
Dmax (cGy)
4021.9±197.9
3871.2±142.4
3499.7±1013.1
0.98 0.48 0.73
Dmean (cGy)
2935.0±353.9
2080.7±318.9
1891.6±701.4
0.02 0.003 0.89
EUD (cGy)
3686.9±63.7
2989.5±158.2
2697.6±845.8
0.12 0.013 0.76
NTCP (×104)
61.3±9.1
10.8±4.4
10.8±9.4
<0.01
<0.01
1.00
Lung
Dmean (cGy)
1244.6±134.1
1422.6±213.0
1467.1±198.05
0.26 0.11 0.97
NTCP
0.0054±0.0027
0.019±0.015
0.022±0.014
0.18 0.06 0.94
V5
47.9±6.1
78.2±13.7
80.8±14.9
<0.01
<0.01
1.00
V10
36.5±4.6
58.6±10.5
67.7±14.0
0.03
<0.01
0.38
V13
33.2±4.2
48.4±8.2
53.0±10.1
0.05
<0.01
0.67
V20
27.5±3.5
24.3±3.7
22.2±3.8
0.30 0.03 0.64
V30
13.2±3.3
8.6±3.3
8.8±3.3
0.04 0.05 1.00
Heart
Dmean (cGy)
2942.5±993.0
2332.4±937.6
2264.4±873.6
0.56 0.48 1.00
EUD (cGy)
3773.8±694.1
3128.5±682.7
3087.6±616.9
0.22 0.18 1.00
NTCP
0.11±0.10
0.021±0.023
0.016±0.017
0.12 0.008 0.99
V25
63.2±23.0
48.4±23.2
40.1±18.5
0.51 0.15 0.86
V30
58.4±22.5
34.7±16.7
28.6±12.8
0.04 0.007 0.88
V50
14.5±8.0
8.7±5.9
8.9±5.6
0.30 0.33 0.88
Body
V5 39.1±8.89.1±8.8
54.4±11.8
58.9±13.5
0.07 0.01 0.87
V10
32.7±7.5
38.2±9.7
43.7±11.5
0.71 0.17 0.71
V15
29.3±6.9
30.2±7.7
28.8±8.5
1.00 1.00 1.00

p=0.04 and p=0.007, respectively. The low dose (V5) delivered to the healthy tissue outside of PTV was increased by IMRT (p=0.07) and VMAT (p=0.01) compared to CRT.