Table 1.

Results in Hounsfield units (HU)

	Baseline		Unilateral Simulation				Bilateral Simulation
	nonO‐MAR		nonO‐MAR		O‐MAR		nonO‐MAR		O‐MAR
VOI	$\mu \left(\mathit{\text{HU}}\right)$	$\sigma \left(\mathit{\text{HU}}\right)$	$\Delta \mu \left(\mathit{\text{HU}}\right)$	$\Delta \sigma \left(\mathit{\text{HU}}\right)$	$\Delta \mu \left(\mathit{\text{HU}}\right)$	$\Delta \sigma \left(\mathit{\text{HU}}\right)$	$\Delta \mu \left(\mathit{\text{HU}}\right)$	$\Delta \sigma \left(\mathit{\text{HU}}\right)$	$\Delta \mu \left(\mathit{\text{HU}}\right)$	$\Delta \sigma \left(\mathit{\text{HU}}\right)$
A	26.6	18.8	$-0.5$	30.5	$-0.3$	13.9	11.3	39.4	5.5	18.2
B	23.0	19.0	2.3	19.0	2.3	7.7	5.4	34.3	2.5	14.7
C	32.4	19.3	0.6	17.5	$-\mathbf{2.0}$	6.2	5.1	33.8	$-\mathbf{1.9}$	13.9
D	33.8	18.9	1.0	14.3	0.6	5.3	13.0	38.5	4.2	17.8
E	32.0	18.8	$-1.2$	13.8	$-\mathbf{2.4}$	5.1	N/A	N/A	N/A	N/A
F	25.3	19.4	2.6	18.6	$-0.4$	7.2	23.1	41.2	11.5	18.3
G	28.3	19.7	$-\mathbf{3.3}$	28.2	$-0.8$	11.3	20.9	38.5	11.8	17.5
H	33.0	18.9	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
I	25.9	15.1	0.3	26.0	0.8	9.8	10.4	30.8	6.0	12.5
J	22.0	17.5	0.9	14.6	0.9	5.5	1.7	23.5	$-0.1$	9.5
K	28.6	15.4	0.4	16.3	$-0.6$	6.3	0.2	24.3	$-0.5$	10.2
L	30.7	15.6	0.3	15.0	0.9	5.5	1.4	24.5	0.2	10.2
M	33.2	15.5	$-\mathbf{1.6}$	15.5	1.2	5.4	2.1	26.4	$-\mathbf{2.0}$	11.5
N	27.4	15.0	0.3	12.6	0.2	4.2	9.9	30.5	4.3	12.9
O	31.9	15.3	$-\mathbf{1.2}$	11.5	$-\mathbf{1.9}$	4.0	$-\mathbf{154.9}$	38.6	$-\mathbf{32.5}$	16.9
P	20.5	16.0	4.1	11.5	1.6	4.3	17.0	36.0	7.2	15.7
Q	26.0	16.4	$-0.1$	15.9	1.2	5.7	2.7	27.1	0.6	11.4
R	25.5	16.0	0.2	17.4	$-\mathbf{1.2}$	7.0	3.0	29.6	$-0.7$	12.5
S	28.6	15.6	0.9	30.6	0.3	13.0	13.3	34.9	4.5	15.7
T	24.7	15.3	$-\mathbf{5.7}$	31.9	$-\mathbf{1.4}$	13.6	$-\mathbf{152.1}$	41.7	$-\mathbf{31.5}$	18.3
U	18.7	26.9	$-\mathbf{4.7}$	27.4	$-1.0$	10.1	$-\mathbf{416.4}$	297.5	$-\mathbf{23.7}$	25.5

For each volume of interest (VOI), the mean CT number (μ) and standard deviation (σ) in the metal‐free baseline are listed, as well as the differences with respect to these values ($\Delta \mu ,\Delta \sigma$) in the other reconstructions. Significant differences in mean CT numbers ($p<0.01$) are printed in bold. For the locations of the VOIs, see Fig. 1(c).

$\mathrm{N}/\mathrm{A}=\text{not applicable}$.