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Contour delineation by the proposed method: (a) original image; (b) manual revision with control points; (c) the manual revised contour (red) and the curve refined contour (green); (d) blue shows the ground truth of the boundary, and green shows the curve refined contour by the proposed method; (e‐f) show parts of curve refinement; (g‐j) show parts of enlarged area in (d).
