Table 2.
Adjusted HRs and 95% CIs for traditional risk factors for severe hypoglycemia (n = 1,206; 185 people with hypoglycemia)
| Model 1 | Model 2 | |
|---|---|---|
| Age, per 5 years | 1.42 (1.25–1.62) | 1.24 (1.07–1.43) |
| Female sex | 0.96 (0.71–1.30) | 1.09 (0.80–1.48) |
| Black race | 1.92 (1.42–2.60) | 1.39 (1.02–1.88) |
| Obese* | 1.46 (1.07–1.97) | 1.31 (0.96–1.78) |
| Fructosamine (vs. lowest tertile) | ||
| Middle tertile (296–350 μmol/L) | 2.30 (1.46–3.62) | 1.78 (1.11–2.83) |
| Highest tertile (>350 μmol/L) | 4.04 (2.62–6.21) | 2.62 (1.67–4.10) |
| Diabetes duration ≥9 years | 1.75 (1.31–2.35) | 1.19 (0.86–1.65) |
| Diabetes medication (vs. none) | ||
| Oral only | 3.01 (1.78–5.07) | 2.20 (1.28–3.76) |
| Any insulin use | 5.51 (3.25–9.34) | 3.00 (1.71–5.28) |
| eGFR <60 mL/min/1.73 m2 (creatinine) | 2.00 (1.35–2.97) | 1.40 (0.92–2.13) |
| ACR | ||
| 30 to <300 mg/g | 1.51 (1.02–2.24) | 1.16 (0.78–1.74) |
| ≥300 mg/g | 3.07 (2.00–4.72) | 1.95 (1.23–3.07) |
| DSST, per 1 lower race-specific SD | 1.67 (1.42–1.96) | 1.57 (1.33–1.84) |
Values are reported as HR (95% CI). Model 1 included age, sex, and race. Model 2 included all variables in model 1 plus all covariates listed in the table.
*Overweight and normal weight were collapsed into one reference group because of the small numbers of normal weight participants.