Table 3.
TBM [n (%)] | No TBM [n (%)] | ORAdjusted (95% CI) | P Value | |
---|---|---|---|---|
Respiratory |
|
|
|
|
Mechanical ventilation | 182 (51.6) | 277 (45.1) | 1.37 (1.01–1.87) | 0.045 |
Cardiopulmonary monitoring | 306 (86.7) | 516 (83.9) | 1.25 (0.82–1.90) | 0.31 |
Supplemental oxygen | 284 (80.4) | 463 (75.3) | 1.23 (0.86–1.75) | 0.25 |
Feeding | ||||
Oral feedings | 96 (30.8) | 168 (33.1) | 0.69 (0.48–1.01) | 0.058 |
Tube feedings | 257 (82.4) | 389 (76.6) | 1.35 (0.90–2.02) | 0.14 |
Medication | ||||
Bronchodilators | 121 (34.3) | 163 (26.2) | 1.50 (1.08–2.12) | 0.02 |
Inhaled steroids | 115 (32.6) | 140 (22.5) | 1.54 (1.09–2.16) | 0.01 |
Any diuretic | 104 (29.5) | 136 (21.9) | 1.36 (0.97–1.89) | 0.07 |
Furosemide | 32 (9.1) | 32 (5.2) | 1.93 (1.08–3.42) | 0.03 |
Spironolactone | 47 (13.3) | 48 (7.7) | 1.67 (1.00–2.77) | 0.05 |
Chlorothiazide | 76 (21.5) | 112 (18.0) | 1.04 (0.72–1.52) | 0.83 |
Antireflux therapy | 151 (42.8) | 208 (33.5) | 1.37 (1.03–1.84) | 0.03 |
Proton pump inhibitor | 113 (32.0) | 158 (25.4) | 1.31 (0.96–1.79) | 0.09 |
H2 blocker | 42 (11.9) | 55 (8.9) | 1.30 (0.82–2.07) | 0.26 |
Pulmonary hypertension therapy | 35 (9.9) | 34 (5.5) | 1.72 (1.02–2.89) | 0.04 |
Definition of abbreviations: CI = confidence interval; OR = odds ratio; TBM = tracheobronchomalacia.
All adjusted models are mixed logistic regressions with bronchopulmonary dysplasia severity, race, sex, insurance status, surfactant use, antenatal steroids use, gestational age, admission age, and birth weight as fixed effects and center as a random intercept.