Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Jan 19;8(7):1203–1215. doi: 10.1080/21505594.2017.1279778

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2017 The Author(s). Published with license by Taylor & Francis

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

PMC Copyright notice

Figure 2. — Endotoxin neutralization by a gal-III specific mAb in vitro. Endotoxin signaling through TLR4 was measured in a cell-based colorimetric assay in the presence of mAb A1102. (A) using purified LPS extracted from 3 isolates expressing gal-III (KP150, KP151, PCM-27). A1102 mAb (red curves), isotype matched control mAb (black curves), or polymyxin B (PMB, blue curves) were used at the indicated concentrations. (B) using shed LPS in supernatants of mid-log phase cultures of ST258 isolates as well as strain PCM-27. (C) Neutralizing potency of A1102 compared with its fragments as well as an aglycosylated (N297Q) version.