Table 1.
Characteristics by site
| United States (n=419) |
Seychelles (n=463) |
Ghana (n=461) |
Overall P- value |
|
|---|---|---|---|---|
| % Male | 51.6 | 48.3 | 42.2 | 0.02 |
| Age (years) | 34.9 (6.2) | †36.0 (5.6) | 34.2 (6.7) | <0.001 |
| Height (cm) | 170.4 (9.0) | †167.4 (8.8) | †162.5 (8.1) | <0.001 |
| Weight (kg) | 92.2 (24.2) | †75.9 (16.9) | †63.4 (11.5) | <0.001 |
| BMI (kg/m2) | 31.8 (8.4) | †27.0 (5.5) | †24.0 (4.5) | <0.001 |
| % BMI ≥30 kg/m2 | 52.2 | †26.1 | †9.9 | <0.001 |
| Estimated GFR (ml/min/1.73m2)c | 134.9 (18.2) | †149.2 (29.1) | †129.8 (19.8) | <0.001 |
| Serum Phosphate (mg/dl) | 3.1 (0.50) | †2.8 (0.45) | †3.4 (0.70) | <0.001 |
| Vitamin D (ng/ml) | 17.3 (8.0) | †29.3 (7.9) | †30.4 (6.9) | <0.001 |
| Plasma FGF23 (RU/mL)a | 57.7 (43.4–75.3) | †42.4 (33.0–55.5) | †33.3 (24.8–47.6) | <0.001b |
†
P<0.01 compared to U.S.
a
Data shown as median (interquartile range)
b
Overall p value calculated by comparing log transformed mean values by site using ANOVA
c
eGFR calculated using the CKD-Epi equation based on cystatin C(23)