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. 2017 Nov 14;89(20):2039–2048. doi: 10.1212/WNL.0000000000004652

Figure 1. Conceptual design of estimating prevalence.

Figure 1

Inverse probability weighting (IPW) adjustment 1 adjusts for nonparticipation in the Mayo Clinic Study of Aging (MCSA); IPW adjustment 2 adjusts for participation in MCSA, but not in imaging studies; standardization involves direct standardization to the Olmsted County 2010 population by age and or sex, where applicable. Of the 5,110 nonparticipants in the MCSA, 1,822 declined the face-to-face evaluation and participated by telephone only; 3,288 refused to participate. A total of 796 people who participated in the face-to-face evaluation were lost to the study prior to August 1, 2008, or were not eligible for imaging.