Table 2.
Characteristic | Group 1 (n = 188) | Normalization
|
P Value* | Group 2 (n = 120) | P Value† | |
---|---|---|---|---|---|---|
Yes (n = 51) | No (n = 137) | |||||
Acute GVHD, n (%)‡ | 57 (30) | 16 (31) | 41 (30) | .86 | 31 (26) | .44 |
Chronic GVHD, n (%) | 53 (28) | 12 (24) | 41 (30) | .47 | 25 (21) | .18 |
PC, n (%) | 80 (43) | 13 (26) | 67 (49) | .005 | 37 (31) | .04 |
Noninfectious PC, n (%) | 14 (8) | 0 (0) | 14 (10) | .01 | 1 (1) | .007 |
Infectious PC, n (%) | 66 (35) | 13 (26) | 53 (39) | .09 | 36 (30) | .39 |
Survival, n (%) | .006 | <.001 | ||||
Alive | 143 (76) | 46 (90) | 97 (71) | 110 (92) | ||
Died | 45 (24) | 5 (10) | 40 (29) | 10 (8) | ||
Death due to PC, n (%) | 12 (6) | 0 (0) | 12 (9) | .04 | 0 (0) | .004 |
PC indicates pulmonary complications.
P value comparing patients in group 1 who did and did not normalize lung function.
P value comparing patients in group 1 and group 2.
Severe acute GVHD grade II-IV.