. 2017 Oct 30;69(12):2303–2313. doi: 10.1002/art.40227

Table 4.

Periodontal pathogen status based on antibody positivity^a

Periodontal pathogen	Pg positive by PCR, % of patients	Anti‐Pg outer membrane antibody levels, mean ± SD μg/ml	Anti‐RgpB at OD450, mean ± SD μg/ml	Anti‐Pi outer membrane antibody levels, mean ± SD μg/ml	Anti‐Fn outer membrane antibody levels, mean ± SD μg/ml
CCP‐2+ (n = 240)	61	106 ± 90	0.3 ± 0.4	145 ± 76	111 ± 115
CCP‐2− (n = 44)	61	96 ± 84	0.3 ± 0.5	146 ± 93	96 ± 74
P	1.000^b	0.365^c	0.495^c	0.564^c	0.308^c
cFIBβ+ (n = 190)	64	112 ± 93	0.4 ± 0.5	150 ± 79	113 ± 124
cFIBβ− (n = 97)	56	94 ± 81	0.3 ± 0.5	137 ± 79	97 ± 72
P	0.195	0.108^c	0.191^c	0.109^c	0.229^c
cVIM+ (n = 92)	65	114 ± 101	0.3 ± 0.4	154 ± 85	120 ± 164
cVIM− (n = 195)	60	102 ± 84	0.4 ± 0.5	142 ± 76	102 ± 70
P	0.37	0.508^c	0.604^c	0.247^c	0.979^c
CEP‐1+ (n = 95)	67	122 ± 98	0.4 ± 0.5	156 ± 81	122 ± 158
CEP‐1− (n = 192)	59	98 ± 84	0.3 ± 0.5	141 ± 78	101 ± 73
P	0.21	0.022^c	0.221^c	0.105^c	0.297^c
cTNC5+ (n = 145)	67	118 ± 96	0.4 ± 0.4	160 ± 78	118 ± 135
cTNC5− (n = 142)	56	93 ± 81	0.3 ± 0.5	131 ± 78	97 ± 73
P	0.068	0.015	0.212^c	0.001	0.109^c
cCK13‐1+ (n = 69)	68	120 ± 99	0.4 ± 0.4	161 ± 81	137 ± 183
cCK13‐1− (n = 218)	60	101 ± 86	0.3 ± 0.5	141 ± 78	98 ± 69
P	0.231	0.197^c	0.230^c	0.050^c	0.078^c

Except where indicated otherwise, chi‐square tests were used to compare frequency distributions of categorical variables. Pg = Porphyromonas gingivalis; PCR = polymerase chain reaction; anti‐RgpB = anti–R gingipain type B; anti‐Pi = anti–Prevotella intermedia; anti‐Fn = anti–Fusobacterium nucleatum; CCP‐2 = cyclic citrullinated peptide 2; cFIBβ = citrullinated fibrinogen β; cVIM = citrullinated vimentin; CEP‐1 = citrullinated α‐enolase peptide 1; cTNC5 = citrullinated tenascin‐C; cCK13‐1 = citrullinated cytokeratin 13–derived peptide 1.

By Fisher's exact test.

By t‐tests and Wilcoxon's rank sum test.