Skip to main content
. Author manuscript; available in PMC: 2018 Dec 1.
Published in final edited form as: Alcohol Clin Exp Res. 2017 Oct 27;41(12):2033–2040. doi: 10.1111/acer.13514

Figure 1. SWI/SNF chromatin remodeling complexes.

Figure 1

A. SWI/SNF complexes result from the combination of core (dark grey), common accessory (light grey), and unique accessory (stipple/PBAF or white/BAF) subunits. More than one gene encodes different versions of many of the subunits: the core ATPase subunit is encoded by SMARCA2 (BRM) or SMARCA4 (BRG1); BAF250 is encoded by ARID1A and ARID1B; BAF155 and BAF170 encode interchangeable core subunits; BAF45A is encoded by PHF10 and BAF45B-D are encoded by DPF1, DPF2 and DPF3; BAF53 is encoded by ACTL6A and ACTL6B; BAF60 is encoded by SMARCD1, SMARCD2, and SMARCD3; BCL7 is encoded by BCL7A, BCL7B, and BCL7C; BCL11 is encoded by BCL11A and BCL11B; SS18 and CREST are encoded by SS18 and SS18L1, respectively. B. BAF complexes purified from neural progenitors (npBAF) and differentiated neurons (nBAF) contain different SWI/SNF subunits; subunits that differ are highlighted with bold lines. npBAF contains BAF53A, BAF45A or BAF45D, and SS18. nBAF contains BAF53B, BAF45B, and CREST.