. Author manuscript; available in PMC: 2019 Mar 1.

Published in final edited form as: J Allergy Clin Immunol. 2017 Jun 1;141(3):1085–1095. doi: 10.1016/j.jaci.2017.02.047

Table 4.

Correlations and shared variances between A-IQOLS, QOLS, and other clinical characteristics, at baseline and at follow-up, n=147.

	A-IQOLS (n=147)						QOLS (n=147)
	Baseline			Follow-up			Baseline			Follow-up
Clinical Characteristic	r*	p	R²	r*	p	R²	r*	p	R²	r*	p	R²
A-IQOLS	-	-	-	-	-	-	−0.39	<.0001	0.15	−0.40	<.0001	0.16
FEV₁ Percent Predicted, pre-bronchodilator†	0.03	0.74	<0.01	−0.004	0.96	<0.01	0.08	0.35	0.0060	0.14	0.09	0.02
ACT	−0.50	<.0001	0.25	−0.53	<.0001	0.28	0.24	0.004	0.06	0.26	0.002	0.07
ASUI†	−0.51	<.0001	0.26	−0.52	<.0001	0.27	0.32	<.0001	0.10	0.26	0.001	0.07
Marks AQLQ	0.74	<.0001	0.55	0.72	<.0001	0.52	−0.48	<.0001	0.23	−0.41	<0.001	0.17
Juniper Mini-AQLQ: Total Score	−0.63	<.0001	0.39	−0.65	<.0001	0.42	0.41	<.0001	0.16	0.32	<.0001	0.10
Symptom Score	−0.58	<.0001	0.33	−0.60	<.0001	0.36	0.38	<.0001	0.15	0.29	0.0003	0.09
PHQ-9	0.45	<.0001	0.20	0.53	<.0001	0.28	−0.52	<.0001	0.27	−0.54	<.0001	0.30
No. of exacerbations requiring OCS‡	0.10$	0.24	0.01	0.21$	0.01	0.04	0.08$	0.36	0.006	−0.19$	0.02	0.04
No. of asthma-related medical visits‖	0.15$	0.06	0.02	0.14$	0.10	0.02	−0.04$	0.67	0.0001	−0.05$	0.53	<0.01

Abbreviations: A-IQOLS, Asthma Impact on Quality of Life Scale; QOLS, Flanagan Quality of Life Scale; FEV₁, forced expiratory volume in one second; ACT, Asthma Control Test; ASUI, Asthma Symptom Utility Index; Marks AQLQ, Asthma Quality of Life Questionnaire; Mini-AQLQ, Juniper mini-Asthma Quality of Life Questionnaire, total score and symptom sub-scale; PHQ-9, Patient Health Questionnaire.

r=Pearson product-moment correlation

^†

Sample size, n=146.

^‡

OCS (oral corticosteroid) prescription of at least 3 days for an asthma-related diagnosis code (asthma, ICD9 493.x; cough, ICD9 786.2; bronchitis, ICD9 490; upper respiratory infection, ICD(465.9; bronchospasm, ICD9 519.11; or wheezing, CD9 786.07) within 4 weeks prior to enrollment. Courses of OCS separated by >7 days were treated as separate exacerbations. See Asthma outcomes: Exacerbations. Fuhlbrigge, A., et al. J Allergy Clin Immunol, 2012:129(3);S34–S48.

Spearman Rank-Order Correlation.

^‖

Outpatient office visit or Urgent Care Clinic visit with asthma-related diagnosis code (ICD9 493.x) within 4 weeks preceding baseline and follow-up assessments. Does not include hospital emergency department visits.