. Author manuscript; available in PMC: 2019 Mar 1.

Published in final edited form as: J Allergy Clin Immunol. 2017 Jun 1;141(3):1085–1095. doi: 10.1016/j.jaci.2017.02.047

Table 5.

Correlations between baseline-to-follow-up changes in asthma status measures and changes in A-IQOLS and QOLS scores, with estimates of shared variance, n=147.

	Change in Characteristic	Association with change in A-IQOLS Score			Association with change in QOLS Score
Clinical Characteristics	Mean ± SD	r*	p	R²	r*	p	R²
FEV₁ Percent Predicted, pre-bronchodilator†	−0.74 ± 8.06	0.10	0.22	0.01	−0.08	0.32	0.01
ACT	0.79 ± 3.16	−0.40	<0.0001	0.16	−0.07	0.40	0.005
ASUI‡	0.04 ± 0.15	−0.33	<0.0001	0.11	−0.02	0.77	0.001
Marks AQLQ	−2.59 ± 7.02	0.52	<0.0001	0.27	−0.005	0.96	<0.01
Mini-AQLQ: Total Score	0.28 ± 0.78	−0.55	<0.0001	0.30	0.07	0.38	0.01
Mini-AQLQ: Symptom Score	0.36 ± 0.93	−0.45	<0.0001	0.20	0.06	0.49	0.003
PHQ-9	−1.03 ± 2.96	0.20	0.01	0.04	−0.16	0.053	0.03
No. exacerbations requiring OCS§	0.01 ± 0.27	0.10‖	0.24	0.01	0.01‖	0.89	<0.01
No. asthma-related medical visits¶	0.04 ± 0.49	0.11‖	0.20	0.01	−0.07‖	0.41	<0.01
A-IQOLS	−0.10 ± 0.37	-	-	-	−0.15	0.07	0.02
QOLS	−0.10 ± 0.61

Abbreviations: A-IQOLS, Asthma Impact on Quality of Life Scale; QOLS, Flanagan Quality of Life Scale; FEV1, forced expiratory volume in one second; ACT, Asthma Control Test; ASUI, Asthma Symptom Utility Index; Marks AQLQ, Asthma Quality of Life Questionnaire; Mini-AQLQ, Juniper mini-Asthma Quality of Life Questionnaire, total score and symptom sub-scale; PHQ-9, Patient Health Questionnaire.

r=Pearson product-moment correlation

^†

Sample size, n=146.

^‡

Sample size, n=146.

^§

OCS (oral corticosteroid) prescription of at least 3 days for an asthma-related diagnosis code (asthma, ICD9 493.x; cough, ICD9 786.2; bronchitis, ICD9 490; upper respiratory infection, ICD(465.9; bronchospasm, ICD9 519.11; or wheezing, CD9 786.07) within 4 weeks preceding enrollment. Courses of OCS separated by >7 days were treated as separate exacerbations. See Asthma outcomes: Exacerbations. Fuhlbrigge, A., et al. J Allergy Clin Immunol, 2012:129(3);S34–S48.

^‖

Spearman Rank-Order Correlation.

^¶

Outpatient office visit or Urgent Care Clinic visit with asthma diagnosis code (ICD9 493.x) within 4 weeks preceding enrollment. Does not include hospital emergency department visits.