Figure 5.

Development of in-stent neoatherosclerosis that caused DES restenosis. A 77-year-old male patient with exertional chest pain showed restenosis (arrow) of Cypher^® DES in the left anterior descending artery (A). OCT evaluation showed lipidic neointima at the site of minimal luminal area (A). Three years prior, this patient underwent OCT evaluation that demonstrated relatively homogeneous neointima without significant luminal narrowing (B). The patient was successfully treated with Xience^® DES implantation.

DES = drug-eluting stent; OCT = optical coherence tomography.