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. 2017 Dec 1;7:16742. doi: 10.1038/s41598-017-17026-5

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The key networks identified by rs-fMRI are detected in both control and HD mice include the primary motor cortex M1 network, secondary motor cortex M2/ cingulate cortex network, striatum network, somatosensory network, retrosplenial cortex network and thalamus network. Z Score from 0 to 8 as indicted by the color bar. The red arrows indicate the seed locations for the subsequent seed-based analysis.