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. 2017 Dec 1;7:16784. doi: 10.1038/s41598-017-17021-w

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Lck expression in CLL cells is not predictive of overall survival or TTFT determined from disease diagnosis in a cohort of patient samples. (a) Kaplan Meier plots showing time to first treatment (TTFT) from disease diagnosis in patients having CLL cells with mutated (M) and unmutated (UM) IGHV genes. (b and c) Kaplan Meier plots showing overall survival and TTFT from disease diagnosis in patients having CLL cells with high or low levels of Lck expression. High and Low Lck expression is determined as being either greater or lesser than the median value (normalized Lck expression of 0.57) for all samples within the cohort.