Fig. 7.

In vivo generation of ILC2₁₀ is associated with reduced eosinophil recruitment. a Rag1 ^−/− mice were injected with the indicated cytokines for four consecutive days and analyzed for lung ILC2 the following day. b, c Compiled data of ILC2 frequency (b) and numbers (c) from Rag1 ^−/− or NSG mice treated as in a. d Rag1 ^−/− mice treated as in a analyzed for lung eosinophils. e, f Compiled data of eosinophil frequency (e) and numbers (f) from Rag1 ^−/− or NSG mice treated as in d. Data are from one (NSG) or four (Rag1 ^−/−) independent experiments with representative plots shown in a, d and compiled data on individual mice shown in b, c, e, f. ***P < 0.001, **P < 0.01, *P < 0.05 and ns (not significant, P > 0.05) (Student’s t test)