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. 2017 Dec 1;7:16747. doi: 10.1038/s41598-017-17140-4

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Network diagram of key carbohydrate metabolism-related DEGs of watermelons in response to CGMMV infection. The EC numbers of key enzymes participating in the carbohydrate metabolism are shown in the boxes. The different colors of the boxes indicate that the enzyme encoding genes were up-regulated (red), down-regulated (green), or slightly changed (white), respectively. The list of key enzymes in the diagram was as following: 2.4.1.82, raffinose synthase; 2.4.1.67, stachyose synthase; 3.2.1.22, alpha-galactosidase (GLA); 2.4.1.13, sucrose synthase (SS); 2.4.1.14, sucrose-phosphate synthase (SPS); 1.1.1.22, UDP-glucose 6-dehydrogenase (UGDH); 3.2.1.26, beta-fructofuranosidase (cell wall invertase); 2.7.1.4, fructokinase; 2.7.1.1, hexokinase (HK); 2.7.7.9, UTP-glucose-1-phosphate uridylyltransferase; 4.2.1.11, enolase (ENO); 2.7.1.40, pyruvate kinase (PK); 4.1.1.1, pyruvate decarboxylase (PDC); 1.1.1.27, L-lactate dehydrogenase (LDH); 1.1.1.1.1, alcohol dehydrogenase (ADH); 4.1.1.49, phosphoenolpyruvate carboxykinase (PEPCK); 6.2.1.1, acetate-CoA ligase (ACS); 1.2.1.3, aldehyde dehydrogenase (ALDH); 5.1.3.6, UDP-glucuronate 4-epimerase; 2.4.1.43, alpha-1,4-galacturonosyltransferase (GAUT); 3.1.1.11, pectinesterase; 3.2.1.67, galacturan 1,4-alpha-galacturonidase; 3.2.1.15, polygalacturonase.