Table 2.

Relationships between podoplanin expression and clinicopathologic factors

Variables	High PDPN expression		Low PDPN expression		p value
	n = 50 (52.6%)		n = 45 (47.4%)
	Number of patients	%	Number of patients	%
PDPN positive area (%)	20.21		6.74		<0.0001
Age (years)	69.2		69		0.926
Sex					0.675
Male	29	58	28	62.2
Female	21	42	17	37.8
Histologic grade					0.241
G1	12	24	16	35.6
G2	33	66	22	48.9
G3	5	10	7	15.6
Tumor size (mm)	28.3		27.5		0.791
Microscopic venous invasion					0.152
Yes	46	92	37	82.2
No	4	8	8	17.8
Microscopic lymphatic vessel invasion					0.141
Yes	40	80	30	66.7
No	10	20	15	33.3
UICC T category					0.569
0	0	0	1	2.2
1	4	8	2	4.4
2	1	2	2	4.4
3	44	88	40	88.9
4	1	2	0	0
UICC N category					0.826
0	20	40	19	42.2
1	30	60	26	57.8
UICC stage					0.521
0	0	0	1	2.2
IA	4	8	1	2.2
IB	1	2	2	4.4
IIA	14	28	15	33.3
IIB	30	60	26	57.8
III	1	2	0	0
Recurrence					0.409
Yes	33	66	26	57.8
No	17	34	19	42.2

Statistical significances were calculated using the student’s t test or the χ ² test

PDPN podoplanin