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Metabolic processes can influence the balance of Th17/T-regulatory (Treg). During development, Treg rely more on fatty acid oxidation (FAO) as the energy source. Otherwise, glycolysis and FAS can promote Th17 differentiation. Several metabolic regulators or enzymes are involved in the balance of Th17 and Treg. Some small molecular compounds of these regulators or enzymes may provide an easy way to further investigate how certain metabolic routes impact the Th17/Treg balance.
