Table 1.
Characteristics and physiologies of IPF patients and the normal
| Characteristic | Normal | IPF | P value |
|---|---|---|---|
| Number | 24 | 24 | / |
| Age(years) | 67.92 ± 7.6 | 69.08 ± 7.1 | / |
| Gender (Male/female) | 13/11 | 13/11 | / |
| FVC (% of predicted) | 89.82 ± 9.8 | 48.72 ± 8.1 | < 0.01 |
| TLC (% of predicted) | 89.14 ± 9.7 | 53.47 ± 8.2 | < 0.01 |
| DLCO (% of predicted) | 89.72 ± 5.9 | 64.05 ± 4.7 | < 0.01 |
| PaO2 (mmHg) | 94.38 ± 4.9 | 77.34 ± 6.1 | < 0.01 |
| PaCO2 (mmHg) | 39.65 ± 4.5 | 36.57 ± 3.8 | / |
| Smoking History (n) | 7 | 18 | < 0.05 |
FVC forced vital capacity, TLC total lung capacity, DLCO diffusing capacity for carbon monoxide; Smoking history denotes subjects with >5 years of cigarette smoking. Two of the seven normal individuals are current smokers. No current smoker in 18 patients with IPF is observed