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PDE4B1-D564A transgenic male mice show increased activity in an open field. Testing was performed for 2 h and activity analyzed for each 15-min block. Data are mean ± SE; asterisks (*) show data from the transgenic mice that is statistically different from that obtained from wild-type mice. a Ambulatory distance, males. b Ambulatory time, males. c Ambulatory distance, females. d Ambulatory time, females. e Vertical time, males. f Vertical time, females
