Table 1.
peptide | [peptide]/μM | [LplA]/μM | yield/%b |
---|---|---|---|
LAP | 60 | 5 | 91 ± 1.5 (n = 3) |
LAP | 60 | 0 | 0 |
Sc. LAP | 60 | 5 | 0 |
0 | 10 | 0 |
General considerations: all reactions performed in 200 μL of PBS + 3 mM ATP + 5 mM Mg(OAc)2 at 30 °C for 10 min and quenched with EDTA (180 mM final concentration) prior to analysis.
Radio-TLC yields measured after treatment of the reaction sample with SDS-PAGE buffer at 95 °C for 5 min. The eluent used was 7:3:0.1 EtOAc:hexanes:acetic acid.