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. Author manuscript; available in PMC: 2017 Dec 15.

Published in final edited form as: Toxicol Appl Pharmacol. 2016 Oct 17;313:47–56. doi: 10.1016/j.taap.2016.10.001

Fig. 6 — A (2 columns). Ingenuity Analysis: Network 1 - Amino Acid Metabolism, Small Molecule Biochemistry, and Cellular Compromise. This pathway demonstrates interactions with metabolites altered in this study and ERK1/2 and NMDA. B (2 columns). Ingenuity Analysis: Network 2 – Increased Levels of Alkaline Phosphatase, Cell Death and Survival, Free Radical Scavenging. This pathway demonstrates interactions with AMPK and Akt.

Fig. 6 — A (2 columns). Ingenuity Analysis: Network 1 - Amino Acid Metabolism, Small Molecule Biochemistry, and Cellular Compromise. This pathway demonstrates interactions with metabolites altered in this study and ERK1/2 and NMDA. B (2 columns). Ingenuity Analysis: Network 2 – Increased Levels of Alkaline Phosphatase, Cell Death and Survival, Free Radical Scavenging. This pathway demonstrates interactions with AMPK and Akt.