Circles and squares correspond to hazard ratios for the effect of Black race, compared to White, on AF. Direct effect is the hazard for AF associated with race after adjustment for baseline PAC burden. % Treatment Effect corresponds to the degree of mediation by baseline PAC burden. Bars represent 95% CIs. *Adjusted for age, sex, body mass index, coronary disease, congestive heart failure, diabetes, hypertension, alcohol consumption, smoking status, and study site.
Abbreviations: AF = atrial fibrillation; CI = confidence interval; HR = hazard ratio; PAC = premature atrial contraction.