α-Actin reactivity in human female reproductive tracts at (A) 9, (B) 11, (C) 12, and (D) 18 weeks. Faint α-actin reactivity first appears focally in mesenchyme of the 9-week uterovaginal canal, increasing in intensity by the 11 weeks. By 12 weeks α-actin reactivity is strong in the middle 2/4ths of the developing reproductive tract, and by 18 weeks, is strongly expressed through the developing female reproductive tract.