Skip to main content
. 2017 Sep 25;82(23):11961–11980. doi: 10.1021/acs.joc.7b02088

Figure 12.

Figure 12

Structure of bleomycin A2, NMR structure of bleomycin bound to a DNA cleavage site (full deoxyoligonucleotide and bleomycin disaccharide removed for clarity), key H-bonding role the pyrimidine C4 amine plays in guanine recognition, and role the minor groove guanine C2 amine plays in the recognition of bleomycin.