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. Author manuscript; available in PMC: 2018 Dec 1.
Published in final edited form as: Mol Cancer Res. 2017 Sep 18;15(12):1667–1677. doi: 10.1158/1541-7786.MCR-17-0333

Figure 2. In vivo IR700 fluorescence imaging of MOC1 and MOC2-luc tumor.

Figure 2

(A) In vivo anti-CD44-IR700 fluorescence real-time imaging of tumor-bearing mice (right dorsum). The tumor showed high fluorescence intensity after injection and the intensity was gradually decreased over days. (B) Quantitative analysis of IR700 intensities in both tumors (n = 10). The IR700 fluorescence intensity of both tumors shows high intensities within 1 day after APC injection but this decreased gradually over days. The overall IR700 intensity over time was significantly higher in MOC2-luc tumors compared with MOC1 tumors at most time points (**p < 0.01, by Mann-Whitney test). (C) Quantitative analysis of TBR in both tumors (n = 10). TBR was high 1 day after APC injection, following which the TBR gradually decreased over the following days in both tumors. TBRs of MOC2-luc tumors were significantly higher than MOC1 tumors at most time points (*p < 0.05, **p < 0.01, by Mann-Whitney test).