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. Author manuscript; available in PMC: 2018 Dec 1.
Published in final edited form as: Mol Cancer Res. 2017 Sep 18;15(12):1667–1677. doi: 10.1158/1541-7786.MCR-17-0333

Figure 3. In vivo effect of NIR-PIT for MOC1 tumor in a unilateral tumor model.

Figure 3

(A) NIR-PIT regimen. Fluorescence images were obtained at each time point as indicated. (B) In vivo IR700 fluorescence real-time imaging of tumor-bearing mice in response to NIR-PIT. The tumor treated by NIR-PIT showed decreasing IR700 fluorescence immediately after NIR-PIT. (C) Tumor growth was significantly inhibited in the NIR-PIT treatment groups (n = 10–14, ***p < 0.001 vs. other groups, Tukey’s test with ANOVA). (D) Significantly prolonged survival was observed in the NIR-PIT treatment group (n = 10–14, ***p < 0.001 vs. other groups, by Log-rank test).