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. 2017 Nov 28;10:393. doi: 10.3389/fnmol.2017.00393

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Copyright © 2017 Chen, Huang, Shentu, Wang, Yan, Zhou, Zhang, Wang, Han, Wang and Cui.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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7Bio attenuates Aβ oligomer-induced increased of CD45 in the hippocampal and cortical region of mice. (A) Representative figures of IHC staining of CD45 in the hippocampal region in various groups as indicated. (B) Quantitative results showed that 7Bio decreased mean OD of CD45 in the hippocampal region of mice. (C) Representative figures of IHC staining of CD45 in the hippocampal region in various groups as indicated. (D) Quantitative results showed that 7Bio decreased mean OD of CD45 in the cortical region of mice. Data represent the mean ± SD (n = 3); ^#p < 0.05 and ^##p < 0.01 vs. control group, ^*p < 0.05 and ^**p < 0.01 vs. Aβ group (one-way ANOVA and Tukey's test). Scale bar: 30 μm.