Table 1.
C4 failure rate by demographic factors and unadjusted and adjusted odds of failing C4 for participants 4 and older.
| Characteristic | No. (%) of participants | Prevalence of C4 failure (95% CI) (%) | p-Value | C4 failure |
|
|---|---|---|---|---|---|
| Unadjusted OR (95% CI) | Adjusted OR (95% CI)a | ||||
| All participants | 1,174 | 11.24 (9.49–13.19) | – | ||
| Sex | |||||
| Male | 465 (39.61) | 13.33 (10.38–16.76) | 0.0728 | 1 (reference) | 1 (reference) |
| Female | 709 (60.39) | 9.87 (7.78–12.31) | 0.71 (0.49–1.04) | 0.59 (0.39–0.89) | |
| Age (years) | |||||
| 4–9 | 201 (17.12) | 10.45 (6.58–15.53) | <0.0001 | 3.20 (1.18–8.69) | 3.04 (1.09–8.44) |
| 10–19 | 283 (24.11) | 6.01 (3.54–9.44) | 1.75 (0.63–4.84) | 1.73 (0.61–4.90) | |
| 20–29 | 184 (15.67) | 5.43 (2.64–9.77) | 1.57 (0.53–4.71) | 1.65 (0.54–4.98) | |
| 30–39 | 142 (12.10) | 3.52 (1.15–8.03) | 1 (reference) | 1 (reference) | |
| 40–49 | 165 (14.05) | 9.70 (5.64–15.27) | 2.94 (1.05–8.24) | 3.04 (1.05–8.74) | |
| 50–59 | 84 (7.16) | 15.48 (8.51–25.01) | 5.01 (1.72–14.62) | 4.37 (1.43–13.40) | |
| 60–69 | 75 (6.39) | 34.67 (24.04–46.54) | 14.53 (5.29–39.99) | 15.35 (5.32–44.33) | |
| ≥70 | 40 (3.41) | 60.00 (43.33–75.14) | 41.01 (13.76–122.62) | 44.60 (14.09–141.17) | |
| Raceb | |||||
| White | 987 (85.01) | 11.35 (9.44–13.49) | 0.5795 | 1 (reference) | 1 (reference) |
| Black or African American | 25 (2.15) | 8.00 (0.98–26.03) | 0.68 (0.16–2.92) | 0.51 (0.10–2.76) | |
| Asian | 80 (6.89) | 7.50 (2.80–15.61) | 0.63 (0.27–1.49) | 0.75 (0.28–2.00) | |
| Other (American Indian, Hawaiian, and more than one race) | 69 (5.94) | 14.49 (7.17–25.04) | 1.32 (0.66–2.66) | 1.33 (0.60–2.94) | |
| Ethnicityc | |||||
| Non-Hispanic | 1,097 (94.24) | 10.94 (9.15–12.94) | 0.1651 | 1 (reference) | 1 (reference) |
| Hispanic | 67 (5.76) | 16.42 (8.49–27.48) | 1.61 (0.74–3.22) | 2.18 (0.99–4.90) | |
aAdjusted for sex, age, race, ethnicity, and history of diabetes, and hypertension.
bData were missing for 13 participants.
cData were missing for 10 participants.
Bold text identifies a statistically significant finding. The p value shown for age (p < 0.0001) is the result of a statistical test comparing all age groups in the same test. When analyzed separately (as pairs), there was no significant difference in the prevalence of C4 failure for the following pairs: 4–9 vs. 10–19, 4–9 vs. 20–29, 4–9 vs. 40–49, 4–9 vs. 50–59, 10–19 vs. 20–29, 10–19 vs. 30–39, 10–19 vs. 40–49, 20–29 vs. 30–39, 20–29 vs. 40–49, and 40–49 vs. 50–59 years (p values between 0.09 and −0.84). The other 16 pairs show a significant difference in the prevalence of C4 failure, with p values ranging from 0.04 to 0.00000001.
OR, odds ratio.