Table 2.
Abbreviations used in this manuscript
| Data set | Size | Description |
|---|---|---|
| SRG | Various | Differentially expressed gene identified by ANOVA time series analysis. SRGs(n) refers to the DEGs conserved in at least n data sets, n = 1,2,…,12 |
| JTG | Various | Gene showing significant up- or down-trend across the time series identified by Jonckheere trend analysis. JTGs(n) refers to the genes with up-trend or down-trend in at least n data sets, n = 1,2,…,12 |
| sgDOCK5-DEGS | Various | Gene signatures differentially expressed during influenza infection scenarios between DOCK5-wt and DOCK5-ko experiments (fold change ≥ 1.2 or ≤ 1/1.2 FDR < 0.05) |
| sgDOCK5-DEG+ | 2863 | A gene signature up-regulated by DOCK5 knockout (i.e., genes repressed by DOCK5) after H3N2 infection (absolute values used, fold change ≥ 1.2, FDR < 0.05) |
| sgDOCK5-DEG- | 4512 | A gene signature down-regulated by DOCK5 knockout (i.e., genes activated by DOCK5) after H3N2 infection (absolute values used, fold change ≤ 1/1.2, FDR < 0.05) |
| DOCK5-CCGS(n) | Table S12 | Genes correlated with DOCK5 in at least n data sets, n = 2, 3,…, 12 |
| GO | 4653 | Gene ontology of biological processes (BP)19 |
| MSigDB | 1329 | Molecular signatures database, curated, canonical processes (c2.cp)20 |
| Watanabe | 129 | Host-factors identified after consensus siRNA studies5 |
| Ward | 280 | Targets after siRNA studies by Ward et al.21 |
| Inflammatome | 2483 | Inflammatome gene set22 |
| ISG | 395 | Interferon Stimulated Genes from the Interferome database23 |
| InnateDB | 1371 | Genes from InnateDB24 |