Table 1.

The eight drug candidates shortlisted from in silico screening and later purchased and evaluated in vitro.

Drug name	ZINC ID	idock score	RF-score v3
Domperidone	19632603	−9.09	7.21
Ketanserin	537877	−9.05	7.10
Oxatomide	19632896	−8.74	6.78
Benperidol	19144237	−8.48	6.93
Cis-flupenthixol	29489118	−8.46	6.77
Canagliflozin	43207238	−8.35	6.69
Indacaterol	35801098	−8.35	6.70
Sildenafil	19796168	−7.28	7.26

The idock score is an estimate of binding free energy in kcal/mol units. A more negative value implies a higher predicted binding stability. The RF-Score v3 is an estimate of binding affinity in negative log scale of Kd or Ki units. A more positive value implies a higher predicted binding affinity.