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Alternate-day fasting (ADF) protected against the increase of Aβ plaques in the cerebral cortex of APP/PS1 mice. (A) Brown immunoreactive plaques indicate the Aβ deposition in the cerebral cortex of mice (bars = 100 μm). (B) The average number of Aβ plaques in the whole cerebral cortex from each section (n = 9 or 10; mean ± SD; one-way ANOVA followed by LSD multiple comparison tests; ∗∗p < 0.01 vs. WT group, ##p < 0.05 vs. AD group; magnify 100×).
