FIGURE 7.

β-Hydroxybutyrate alleviated the decrease of miR-130a expression and the increase of HDAC3 expression in Aβ-exposed U251 cells. The relative expression of miR-130a (A; U6 as a reference standard), HDAC3 mRNA (B; β-actin as a reference standard), and proteins (C,D) were analyzed by qRT-PCR and Western blot, respectively [n = 6; mean ± SD; one-way ANOVA followed by LSD multiple comparison tests; ^∗p < 0.05, ^∗∗p < 0.01 vs. control group, ^#p < 0.05, ^##p < 0.01 vs. Aβ (2 μM) group, ∆∆p < 0.01 vs. Aβ (10 μM) group].