Table 2.
Hemodynamic and physiologic parameters before (0 h) and 4 h after sevoflurane exposure.
| MBP (mmHg) | HR (beat/min) | pH | PaCO2 (mmHg) | PaO2 (mmHg) | SaO2 (%) | |
|---|---|---|---|---|---|---|
| 0 h | ||||||
| Wistar+CON | 100 ± 2 | 329 ± 18 | 7.41 ± 0.05 | 38.2 ± 3.1 | 163 ± 12 | 98.6 ± 2.2 |
| Wistar+SEV | 101 ± 4 | 332 ± 15 | 7.40 ± 0.04 | 40.1 ± 3.5 | 162 ± 17 | 98.1 ± 3.9 |
| GK+CON | 119 ± 5∗ | 330 ± 11 | 7.39 ± 0.05 | 39.7 ± 3.0 | 166 ± 19 | 98.5 ± 2.7 |
| GK+SEV | 121 ± 4∗ | 335 ± 13 | 7.40 ± 0.04 | 40.4 ± 3.3 | 160 ± 14 | 98.3 ± 3.0 |
| 4 h | ||||||
| Wistar+CON | 97 ± 5 | 320 ± 16 | 7.39 ± 0.06 | 38.5 ± 3.9 | 162 ± 15 | 98.8 ± 3.3 |
| Wistar+SEV | 99 ± 3 | 328 ± 20 | 7.38 ± 0.05 | 39.1 ± 3.7 | 161 ± 12 | 98.2 ± 3.4 |
| GK+CON | 120 ± 6∗ | 327 ± 14 | 7.41 ± 0.05 | 39.2 ± 3.4 | 163 ± 16 | 98.6 ± 3.6 |
| GK+SEV | 117 ± 5∗ | 325 ± 19 | 7.39 ± 0.04 | 40.0 ± 3.5 | 165 ± 18 | 98.5 ± 4.2 |
MBP, mean blood pressure; HR, heart rate; PaCO2, arterial carbon dioxide tension; PaO2, arterial oxygen tension; SaO2, arterial oxygen saturation. Data are presented as mean ± SE (n = 6–10 for each group), ∗P < 0.05 versus respective Wistar rats at the same time point.