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. 2017 Oct 13;292(48):19556–19564. doi: 10.1074/jbc.M117.804914

Table 1.

Q10 coefficients for extracellular (exo) and intracellular (endo) metabolites

Metabolite Q10 R2
5-Oxoprolinea (exo) 1.28 0.69
l-Glycerate (endo) 1.84 0.52
S-Adenosylmethioninamine (endo) 1.94 0.83
l-Glutamate (endo) 2.01 0.94
cis-Aconitate (endo) 2.06 0.91
l-Glutamate (exo) 2.15 0.99
l-Aspartate (endo) 2.18 0.73
Nicotinamidea (exo) 2.19 0.91
Mannitol (exo) 2.22 0.86
Uridine (exo) 2.27 0.94
Citrate (exo) 2.32 0.99
l-Glutamine (endo) 2.34 0.90
Reduced Glutathione (exo) 2.39 0.99
Choline (endo) 2.41 0.85
GMP (endo) 2.42 0.97
5-Oxoproline (endo) 2.56 0.98
Lactate (endo) 2.61 0.98
l-Acetylcarnitine (endo) 2.62 0.72
Xanthine (endo) 2.65 0.84
cis-Aconitate (exo) 2.75 0.91
Phosphorylcholine (endo) 2.75 0.89
Lactatea (exo) 2.78 0.99
Uridine (endo) 2.79 0.96
Glucosea (exo) 2.81 0.98
AMP (endo) 2.96 0.79
Adeninea (exo) 2.98 0.93
l-Serine (exo) 2.99 0.99
S-Adenosylhomocysteine (endo) 3.01 0.83
Malate (endo) 3.02 0.97
Oxidized glutathione (endo) 3.03 0.95
l-Carnitine (exo) 3.04 0.97
5-Methylthioadenosine (endo) 3.07 0.73
Adenine (endo) 3.17 0.95
Glucose 6-phosphate (endo) 3.19 0.97
l-Glutamine (exo) 3.23 0.99
l-Phenylalanine (exo) 3.33 0.75
IMP (endo) 3.45 1.00
l-Lysine (exo) 3.46 0.96
Chloride ion (exo) 3.94 0.99
ATP (endo) 3.95 0.92
l-Histidine (exo) 4.07 0.89
ADP (endo) 4.48 0.84
6-Phosphogluconate (endo) 4.84 0.79
Oxidized glutathione (exo) 4.99 0.95
Malatea (exo) 5.05 0.99
l-Lysine (endo) 5.18 0.97
Reduced glutathione (endo) 5.61 0.96
Hypoxanthine (endo) 5.89 0.95

a Previously reported biomarker (20).