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. Author manuscript; available in PMC: 2018 Oct 1.
Published in final edited form as: Ann Allergy Asthma Immunol. 2017 Oct;119(4):317–323.e1. doi: 10.1016/j.anai.2017.07.024

Figure 4.

Figure 4

H&E staining of sinus tissue. A. Normal control: Normal sinonasal mucosa lined by ciliated pseudotratified, columnar epithelium with identifiable mucocytes (goblet cells) with underlying seromucous glands scattered throughout the submucosa. Magnification 200x B. CRSsNP: Submucosal edema with mixed inflammatory cells, including mature lymphocytes with variable plasma cells, eosinophils, histiocytes, and neutrophils. Magnification 200x. C. CRSwNP: The surface epithelium is composed of intact respiratory epithelium. The underlying stroma is markedly edematous and is noteworthy for the absence of seromucous glands. A mixed chronic inflammatory infiltrate is present and is predominantly composed of eosinophils, plasma cells, and lymphocytes. Magnification 100x D. Lymphoid follicle: Dense and sizable (>50 lymphoid cells) aggregate with predominantly lymphoid cells (i.e. other chronic inflammatory including plasma cells, eosinophils, histiocytes, and neutrophils cells constitute only a minor subset within the aggregate). All other lymphoid patterns are considered a part of the chronic inflammatory infiltrate. Magnification 400x.