Figure 3.

Effect of aqueous extracts from the leaves of Aspidosperma pyrifolium and rutin on inflammation in carrageenan-induced peritonitis model. BALB/c mice were treated intravenously with: aqueous extracts at doses of 2, 10 or 40 mg/kg (A); or rutin at doses of 2, 2.5 or 5 mg/mL (B), and immediately injected with 1 mL carrageenan 1% intraperitoneal. Dexamethasone (Dexa) at the dose of 0.5 mg/kg was used as positive control intraperitoneal. After four hours, the peritoneal wash was performed with PBS and the number of cells was determined using a Neubauer chamber. *** p < 0.001, ** p < 0.01 and * p < 0.05 when compared to the venom group. Data were analyzed using ANOVA followed by Tukey Test. Dexa: dexamethasone (0.5 mg/kg) and Sal: saline.