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. 2017 Oct 27;18(11):2261. doi: 10.3390/ijms18112261

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© 2017 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effect of selective P2X receptor antagonists on Tg-resistant ATP-evoked Ca²⁺ response in THP-1 differentiated macrophages. (A,B) effect of P2X₄ receptor antagonist (10 μM 5-BDBD) on magnitude of Ca²⁺ response and net calcium movement on Tg-resistant Ca²⁺ response (n = 3); (C,D) effect of P2X₄ receptor antagonist (10 μM PSB-12062) on magnitude of Ca²⁺ response and net calcium movement on Tg-resistant Ca²⁺ response (n = 3); (E) effect of P2X₇ receptor antagonist (5 μM A438079) represented as time response traces (n = 3); (F) effect of P2X₁ receptor antagonist (30 μM Ro0437626) represented as time response traces (n = 3). Asterisks include significant changes towards control (*** p < 0.001, ** p < 0.01).