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Dietary-induced changes and the effect of metformin on weight control. Overall design in experimental animals. (A) Values obtained in mice upon feeding with experimental diets for 14 weeks. CD, chow diet; HFD, high-fat diet; (B) values obtained after a 6 week period of HFD feeding and shift to CD. Asterisks denote significant (p < 0.05) changes compared to the respective group.
