Table 1.

Expression levels of HS biosynthesis-involved genes in glioma.

Gene ID	Primary Source	Gene Name	Description	Para-Tumourous Tissue	Grade II-III	Grade IV
2131	HGNC:3512	EXT1	Exostosin Glycosyltransferase 1	54.9 ± 58	8.2 ± 8.38	3.4 ± 2.1
2132	HGNC:3513	EXT2	Exostosin Glycosyltransferase 2	41.5 ± 54	35.5 ± 54	8.7 ± 5.7
3340	HGNC:7680	NDST1	N-deacetylase and N-sulfotransferase 1	6.2 ± 2	4.5 ± 7	3.2 ± 6
8509	HGNC:7681	NDST2	N-deacetylase and N-sulfotransferase 2	25.5 ± 4	12.4 ± 8	11.6 ± 14
26035	HGNC:17855	GLCE	Glucuronic Acid Epimerase	0.001 ± 0.001	0.005 ± 0.008	0.002 ± 0.001
9653	HGNC:5193	2OST1/HS2ST1	Heparan Sulfate 2-O-Sulfotransferase 1	1.12 ± 1.4	1.6 ± 1.33	1.58 ± 1.1
9957	HGNC:5194	3OST1/HS3ST1	Heparan Sulfate-Glucosamine 3-O-Sulfotransferase 1	0.8 ± 1.0	2.05 ± 1.3	0.81 ± 1
9956	HGNC:5195	3OST2/HS3ST2	Heparan Sulfate-Glucosamine 3-O-Sulfotransferase 2	0.84 ± 0.35	0.22 ± 0.31	0.24 ± 0.39
9394	HGNC:5201	6OST1/HS6ST1	Heparan Sulfate 6-O-Sulfotransferase 1	66.6 ± 13.9	43.6 ± 49	11.2 ± 11
90161	HGNC:19133	6OST2/HS6ST2	Heparan Sulfate 6-O-Sulfotransferase 2	86.8 ± 19	42.6 ± 43	39.3 ± 77
23213	HGNC:20391	SULF1	Sulfatase 1	2.01 ± 2.1	1.2 ± 1.3	0.56 ± 0.88
55959	HGNC:20392	SULF2	Sulfatase 2	0.37 ± 0.44	0.37 ± 0.43	0.85 ± 0.81
10855	HGNC:5164	HPSE	Heparanase	0.51 ± 0.007	0.39 ± 0.058	0.44 ± 0.35