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. 2017 Nov 8;18(11):2369. doi: 10.3390/ijms18112369

Figure 6.

Figure 6

Na, K-ATPase β subunit isoforms functional fates. (1) as a subunit of the plasma membrane sodium pump αβ protomer [16]. (2) as a component of the cell de-differentiation and proliferation regulatory path Src-B-Raf-MEK-ERK [25]. (3–4) transcriptional regulator as co-activator of RNA polymerase II, embedded either in the nuclear envelope (3) or intranuclear (4). (5) in the cytosol, ready to be disposed to the plasma membrane or, (6) to act as an adaptor of a transduction signal canonical pathway or, (7) constituting a piece of the podosome/invadosome system.