Table 2.
Cell- and subcellular-specific Na, K-ATPase β subunit isoforms expression in primary and secondary GBM.
| Primary GBM | β1 | β2 | β3 |
| Astrocytes | −/+ c,n |
++ c,n,m |
++ n |
| Endothelial cells | −/+ c |
++ c,n |
++ n |
| Pericytes | ++ c,m |
++ c,n |
++ c,m |
| Telocytes | ? | +++ c,n |
+++ c |
| TAMs | ++ m |
++ c,n |
++ c,m |
| Tumor cells | −/+ c,n,m |
+ c,n,m |
+++ c,n |
| Secondary GBM | β1 | β2 | β3 |
| Astrocytes | − | −/+ c,n,m |
+++ c,n,m |
| Endothelial cells | + c,m |
++ c,n |
+++ n |
| Pericytes | +/++ c,m |
? | ++ c,m |
| Telocytes | − | +++ c,n |
+++ c,n |
| TAMs | + c,n,m |
++ c,n |
++ c,m |
| Tumor cells | −/+ c,n |
+ c,m,n |
+++ n |
−, negative; +, low; +, moderate; +++, high; −/+, variable from low to absent; ++/+, variable from moderate to low; ?, indeterminate staining; m, membrane; c, cytoplasm; n, nucleus or nuclear envelope. TAMs: tumor associated macrophages.